Drug guides / Systemic HRT decisions
Prometrium vs generic progesterone: verify the capsule and ingredients
At a glance
Compare Prometrium with the exact generic progesterone capsule, strength and prescribed schedule. Both cited records include peanut oil. “Generic” does not mean peanut-free, and the two label records alone do not certify the substitution status of every supplier. Prometrium source · Generic progesterone source

Product facts behind the comparison
| Product | Ingredient | Form | Labeled role |
|---|---|---|---|
| Prometrium | micronized progesterone | Oral capsule | Endometrial hyperplasia prevention with estrogen in the labeled population Prometrium source |
| Generic progesterone | micronized progesterone | Oral capsule | Endometrial hyperplasia prevention with estrogen under this label Generic progesterone source |
Routine and safety questions
- Prometrium: Use the prescribed strength and cycle. Cited capsules contain peanut oil; allergy and exact formulation matter. Prometrium source
- Generic progesterone: Use the prescribed strength and cycle. The cited generic also contains peanut oil; verify the actual dispensed supplier. Generic progesterone source
These schedules summarize label information for comparison, not instructions to start, stop or change a prescription. Contraindications, interactions and other warnings are not exhaustively listed here. Follow the actual prescription and read the linked full label.
Which generic capsule and ingredient list were checked?
| Check | Prometrium | Cited generic record |
|---|---|---|
| Ingredient comparison | Micronized progesterone capsules; verify the prescribed strength. | Banner Life Sciences LLC progesterone capsule record, with 100 mg and 200 mg strengths. |
| Allergy-relevant finding | The cited label lists peanut oil. | The cited generic label also lists peanut oil. Generic does not mean peanut-free. |
| Availability limit | A published brand label is not a stock check. | DailyMed flags inactivated NDC codes in this record. It must not be presented as proof of a currently available supplier. |
| Before accepting a quote | Record strength, capsule count and prescribed cycle. | Ask for the actual supplier/NDC, current ingredient leaflet and pharmacy confirmation of substitution. |
This is a bounded label comparison, not a verification of every generic on sale. A different dispensed supplier needs a fresh ingredient and substitution check. For budgeting, compare the same prescribed cycle rather than assuming every plan uses a capsule every day.
How to use this comparison
Take the brand and generic names, strength and supplier to the pharmacist. Request the current ingredient list for the actual dispensed product if you have an allergy concern. For budgeting, count the capsules required by the prescribed schedule instead of assuming every progesterone plan uses the same quantity each month. Ask for brand and generic prices using identical days supplied. Keep this comparison tied to the role in your estrogen plan; it is not a recommendation to start progesterone for sleep.
Questions about this decision
Is the cited generic peanut-free?
No. The cited generic and Prometrium labels both list peanut oil.
Can the capsule schedule change the cost?
Yes. Quote the amount required by your actual prescription rather than an assumed monthly quantity.
Does this guide recommend progesterone for insomnia?
No. Its scope is the labeled role shown in the table and the prescribed regimen.
What should the pharmacist confirm?
The actual supplier, strength, ingredients and substitution eligibility.
What this guide does not establish
No head-to-head superiority, automatic substitution, pharmacy stock, personalized insurance coverage or guaranteed savings is established here. A label source supports the specific product facts cited; it does not endorse this website or validate a calculator result.
Related decisions
Sources and verification scope
- Prometrium — label or manufacturer information
Used for: Indications; ingredients; contraindications. Selected facts checked 2026-09-15. No pharmacy stock or personal coverage verification. - Generic progesterone — label or manufacturer information
Used for: Indications; ingredients; contraindications. Selected facts checked 2026-09-15. No pharmacy stock or personal coverage verification.
Editorial synthesis connects the cited facts to practical questions. Sources were checked for the selected facts, not audited for every possible warning. Current pharmacy quotes and independent clinical review are still outstanding.
Machine-readable answer and evidence record (JSON)
Related comparison: Prometrium vs Provera: progesterone and medroxyprogesterone tablets.